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Based on the number of FDA Adverse Events reports received for this unusual side effect, the FDA is monitoring all the GLP-1 drugs for possible regulatory action related to the side effect

These include larger registration studies such as ATTAIN-HYPERTENSION and smaller studies to evaluate blood pressure alongside weight loss, such as SOLUTION-Pilot

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Most users report noticing significant changes around the 4-6 week mark, with continued improvements over 3-6 months of consistent use