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On the other hand, dysbiosis can alter the production of BAs, causing changes in lipid metabolism and increasing the risk of atherosclerosis (Jonsson and Bckhed, 2017)
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In human muscle cell studies 4 , IGF-1 directly increased myotube nuclei, fusion index, and myosin heavy chain content, all key indicators of muscle growth
doi: 10.1038/nature25003 46