The caloric deficit from the drug plus exercise can be aggressive, listen to your body and adjust intensity as needed
Results were even more compelling in the second trial, where patients were already utilizing PAP therapy
And in my experience with complex patients, the mast cell, POTS, and chemically sensitive populations who cannot tolerate aggressive pharmaceutical interventions under any circumstances, this gentler approach has made GLP-1 therapy accessible to people who would have been completely excluded from it at standard doses
Excess weight, in and of itself, is not a disease. When it comes to her patients, she says, shes a stickler for a holistic approach to health, including eating a nutritious diet (not just eating less) and daily physical activity, as essential elements of the weight-loss process
When to seek medical advice : Contact your GP or diabetes specialist promptly if you experience: Severe, persistent vomiting or diarrhoea leading to dehydration Severe abdominal pain, particularly if radiating to the back (potential pancreatitis) Signs of hypoglycaemia (if taking insulin or sulphonylureas concurrently) Symptoms of gallbladder problems (pain in the upper right abdomen, fever, yellowing of skin) Any changes in vision (rapid improvement in blood glucose can sometimes worsen diabetic retinopathy) [20] Unexplained persistent nausea beyond the first few weeks If you are planning pregnancy, discuss this with your healthcare provider as GLP-1 RAs are not recommended during pregnancy or breastfeeding