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Mahmoud Nassar, MD, PhD, from the Department of Medicine, Division of Endocrinology, Diabetes and Metabolism at the Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, who was not involved in this research, noted the following about the study to Medical News Today : Using national Medicare data, the study employs a robust target trial emulation design and leverages rigorous propensity score matching to balance demographic and clinical factors
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The authors explicitly frame their own finding as relevant to the injection question: topical application, they note, "may offer an effective alternative to injection," comparing the quantity of copper made bioavailable through a realistic topical patch against a reference subcutaneous injection dose used in animal research
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With proper screening and provider oversight, long-term use remains safe
Benefits of lixilan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide, versus insulin glargine and lixisenatide monocomponents in type 2 diabetes inadequately controlled on oral agents: the LixiLan-O randomized trial
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