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Our related article on GLP-1 Signaling, the Microbiome, and Hormones explains why GLP-1 biology is part of a larger metabolic network rather than a stand-alone weight-loss switch

Mol Metab 30:72130 Kabahizi A et al (2022) Glucagon-like peptide-1 (GLP-1) signalling in the brain: from neural circuits and metabolism to therapeutics

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Originally developed as diabetes medications, semaglutide and tirzepatide are often prescribed for weight loss GLP-1 (glucagon-like peptide-1) receptor agonists are medications that mimic the GLP-1 hormone, which helps regulate blood sugar levels and appetite