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For instance: people with obesity are more likely to develop type 2 diabetes people with obesity are at an increased riskof developing Alzheimers later in life people with type 2 diabetes are also more likely to develop Alzheimers disease Alzheimers disease is associated with insulin resistance in the brain, with some scientists referring to Alzheimers as type 3 diabetes obesity, type 2 diabetes, and Alzheimers all involve inflammation, and GLP-1 agonists have an anti-inflammatory effect studies in animal models of dementiahave shown that GLP-1 agonists can protect rats brains from damage

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J Biol Chem 282:1842736 Pineda-Molina E, Klatt P, Vazquez J, Marina A, Garcia DL (2001) Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding

Newer research suggests the muscle loss concern may have been overstated in some early studies

Oral drugs are designated as orange dots, and blue designates the injectable treatments