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Lithium, tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs), antiepileptics, rifampin, metformin, and amiodarone mainly affect directly thyroid function

"Effect of Methylsulfonylmethane Pretreatment on Aceta-minophen Induced Hepatotoxicity in Rats"

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Zinc can also cause pancreatitis depending on the dose, but in the case reported, the authors attributed the AP to the use of the arginine supplement, warning doctors and trainers to be cautious when prescribing this supplement [83]