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In the SURPASS clinical trial program for type 2 diabetes, patients achieved HbA1c reductions of 1.9% to 2.6% depending on dose, with weight loss averaging 15-22 pounds across studies

Foci of cellular alteration can occur spontaneously in aged rats and other rodents and can be induced by chemical treatment

So today, I want to briefly walk through the 340B program itself, how it started, how it has changed over time, and then review what we learned from Minnesota in the first report before really going into this newer report

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