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Therefore, this study investigated the metabolic profiles of patients with MMA carrying MUT mutations to identify candidate biomarkers and altered pathways that may improve our understanding of MMA pathophysiology and support future diagnostic applications

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For optogenetic manipulation, the intensity of the blue light (473 nm, 2.5 mW, 10 ms, 20 Hz) or the yellow light (594 nm, 5 mW, 10 ms, 20 Hz) was measured and determined by the photometer and then controlled by the device (QAXK-LASER, ThinkerTech, China)

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