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A body mass index (BMI) of 35 or more

These drugs also simultaneously decrease levels of an enzyme called DPP-4, which inactivates GLP-1

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In addition, recent clinical evidence from the AngioSafe T2DM Study demonstrated no association between GLP-1 RAs and severe diabetic retinopathy [107], suggesting that GLP-1 RA does not have a causal influence on retinopathy independent of glucose lowering