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Furthermore, coffee consumption epidemiological studies often fail to include information on the genetic type and source of coffee beans, the type and brand of coffee, the blend and mode of preparation, the caffeine or another physiologically active or toxic component concentration, and the volume of coffee per serving
Peripheral neuropathy, subacute combined degeneration of the spinal cord, or cognitive impairment indicate more advanced deficiency and generally require intensive treatment over extended periods
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J Pharmacol Sci 108:717 Klicek R, Kolenc D, Suran J et al (2013) Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability
Its half life is also very short, measured in minutes, making it face similar challenges and considerations in research protocol design as GHK-Cu
