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Clinical trials at doses up to 40mg daily for 12 weeks have reported no serious adverse effects (Brendler & Williamson, 2019, Phytomedicine )

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The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88

A licensed registered nurse will administer and oversee the IV therapy