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They require ongoing monitoring

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The study included 521 patients and HbA1c was reduced by sitagliptin from 7.7% (61 mmol/mol) to 7.1% (54 mmol/mol), again with low risk for hypoglycemia and no weight gain

However, it is important to note that: Clinical trials have limitations in detecting rare adverse events, particularly those that may take extended periods to develop Post-marketing surveillance continues to monitor for previously unidentified safety concerns Individual case reports may emerge, but these do not establish causation without rigorous epidemiological analysis Why the question arises : The association between Wegovy and diverticulitis may be questioned because: Gastrointestinal effects : Wegovy commonly causes GI side effects including nausea, constipation, and changes in bowel habits, which might theoretically affect colonic function

"Meta-analysis of randomised controlled trials with N-acetylcysteine in schizophrenia." Aust N Z J Psychiatry