Costello, J
Both examples are characterised by contextual conditions that are so the assumption rather hostile to sustainability transformation: Structural weakness, shrinking dynamics, brain drain and capacity reduction in the past, negative transformation experiences in the course of deindustrialisation and socio-political upheavals
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Thus, cytosolic HSP70 may affect proteostasis in the ER in the absence of active GRP78 isoforms, although the distinct mechanisms involved remain to be elucidated
We can have a life-long impact on thousands of patients if we learn to recognize the implications of the various thyroid dysfunctions and help patients better understand their treatment options