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FIGURE 2 FIGURE 3 Shape Similarity Screening Shape similarity screening was done with the Rapid Overlay of Chemical Structures (ROCS) tool (version 3.2.2.2) from OpenEye Scientific software package (McGann, 2012) and the ChemBridge Hit2Lead library

Ethics statement The animal study was approved by the Ethical Committee of the Faculty of Medicine, Ain Shams University

Dual role of LC in human health, insights of beneficial short term usage and potentially harmful long term complications F/B: Firmicutes-to-Bacteroidetes

Conversely, when fluid intake is inadequate or fluid losses are excessive, the kidneys conserve water by producing more concentrated urine, which appears darker yellow or amber

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