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Phase I reaction These are non-synthetic reactions that introduce a hydrophilic group or unmask the already present hydrophilic group in these drugs

doi: 10.3389/fcell.2026.1851623 Received 09 April 2026 Revised 21 June 2026 Accepted 01 July 2026 Published 27 July 2026 Volume 14 - 2026 Edited by Erja Kerkel, Finnish Red Cross Blood Service, Finland Reviewed by Guifang Zhao, Mayo Clinic, United States Yoshihiro Kushida, Tohoku University, Japan Updates Copyright 2026 Xiao, Guo, Shao, Xie and Huang

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Several probiotics and prebiotics have been shown to have positive effects on sleep, which could be interpreted to mean that sleep health can be managed by supporting the MGBA (Thompson et al., 2020)