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Antidepressants and anti-seizure medications may be prescribed for chronic pain, according to the Mayo Clinic

That distinction is important

Higher doses (90 mg and 120 mg) achieved up to 12.2% mean reduction from baseline (26.6 lbs) versus 1.3% (2.9 lbs) for placebo, with up to 97% of patients losing 5% of body weight

Take before meals or when nausea hits

Perspectives on clinical impact and adherence The World Health Organization defines adherence as the extent to which a persons behaviortaking medication, following a diet, and/or executing lifestyle changes, corresponds with agreed recommendations from a health care provider [68]