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J Clin Med (2020) 9(8):28

Physiological Effects of GIP in the Body GIP was first thought to act solely as an inhibitor of gastric acid secretion hence the older name gastric inhibitory polypeptide. However, modern science has shown it plays far more important metabolic roles , especially in: 1

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The pathophysiology of neuropathic pain varies and includes ectopic activity in damaged nerves or in adjacent nerves, dorsal root ganglion (DRG) or central pathways, and peripheral and central sensitisation involving numerous molecular mechanisms

For mild dietary deficiency with normal absorption, oral supplements or dietary changes may be sufficient