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It is not intended as nutritional or medical advice for individual problems

In addition, a therapeutic dose of Phyllanthus urinaria showed no toxicological phenomena in mice

Calcium, ischemia and excitotoxicity

A narrative review concluded that the practice is controversial because there are no standardized dosing protocols and nearly onethird of patients report adverse effects, ranging from mild gastrointestinal symptoms to liver dysfunction and lifethreatening allergic reactions

[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment