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Skin Penetration and Depot Formation An ex vivo human skin penetration study measured a permeability coefficient of 2.43 x 10^-4 cm/h for copper tripeptide, with 82 micrograms per square centimeter retained in dermal tissue as a depot over 48 hours (PMID 20703511)

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C.ColosioC.GrandjeanP.et al (2012)

These pleiotropic effects have raised interest also in the field of dermatology and phytotherapy, so an application for vitiligo was hypothesized