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(2001) Cellular distribution and function of soluble guanylyl cyclase in rat kidney and liver J

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Keywords: Reactive oxygen species, Redox signaling, Oxidative stress, NADPH oxidases (NOX/DUOX), Mitochondrial ROS, Reverse electron transport, Endoplasmic reticulum, Peroxisomes, Peroxiredoxins, RNS/RSS crosstalk, Ferroptosis, Peroxynitrite, Redox biomarkers Introduction Reactive oxygen species (ROS) are a heterogeneous group of molecules derived from the partial or complete reduction of oxygen, most notably superoxide (O 2 ), hydrogen peroxide (H 2 O 2 ) and the hydroxyl radical ( OH)