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If you're not getting enough B12, you can experience anemia, fatigue, weakness, constipation, decreased appetite, weight loss, dizziness, lightheadedness, confusion, poor memory, soreness of your tongue and mouth, and tingling and numbness in your hands and feet, according to Harvard Health Publishing

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others notice benefits over a few hours

This review looks at the molecular composition, mechanism of action and research applications of both substances, essential information for researchers in this field