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doi: 10.1016/S0165-3806(98)00047-9 154 MalaebSNStonestreetBS

The SURPASS-CVOT trial is evaluating major adverse cardiovascular events in at-risk populations, driven by the recognition that metabolic interventions capable of reducing weight and improving glycaemic control may also influence cardiovascular risk trajectories

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Similarly, substituting the ethoxy group at position R 2 with the smaller methoxy ( 28 ) or hydroxy ( 29 ) groups did not hinder solubility but reduced binding to TRF1 TRFH in the CPMG assay