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Continuous GLP-1RA Use Reduces MACE Risk Incident use of GLP-1RAs was associated with a lower risk of MACE compared to incident use of sulfonylureas

At PEAK, Contrave is prescribed as part of a clinical treatment program often as a step therapy medication or alongside other approaches in a medication plan

Some weight regain is common after stopping GLP-1 therapy because appetite hormones return to baseline, but research shows most patients maintain 5070% of their weight loss long-term if they sustain healthy habits

This glucose-dependent mechanism is what makes them so safe your blood sugar cannot crash because the drug automatically switches off at normal glucose levels

If you're taking GLP-1 medications, alcohol may also worsen side effects like nausea, heartburn, or stomach discomfort in some people