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Yang et al., 2014)

In vitro experiments further confirmed that Rg3 treatment increased ULK1 and FUNDC1 expression in oxygen-glucose deprivation/reperfusion (OGD/R)-treated rat cardiomyocytes, triggered the phosphorylation of FUNDC1 at the Ser17 site via ULK1 to activate mitophagy, and facilitated FUNDC1-LC3 interactions, which resulted in the maintenance of mitochondrial homeostasis and energy metabolism and ameliorated HF (Wang X

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Easy measuring: At 16.67 mg/mL, 1 U-100 unit = 0.01 mL = approximately 166.7 mcg