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Caloric intake will need to increase, but making it gradual and very intentional with the types and quantity of food will help to slow weight regain without feeling too hungry

Metabolic Support Peptides, such as tirzepatide found in Zepbound, also enhance metabolism and reduce fat storage, supporting increased weight loss results

Beyond appetite regulation, GLP-1 plays a critical role in blood sugar management

GIPR antagonism exemplified by AMG 133 (maridebart cafraglutide) pursues the opposite strategy: blocking GIPR in adipose tissue while activating GLP-1R, based on observations that GIP promotes lipid storage in adipocytes under hyperinsulinemic conditions

Its targeted fat-burning effects are ideal for individuals looking to improve fat distribution and body composition