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Semaglutide is a glucagon-like peptide-1 agonist that works on the GLP-1 receptors in the body to reduce appetite by delaying gastric emptying

[76] [77] Other mammalian species (examples: rabbits, pikas, beaver, guinea pigs) consume high-fiber plants which pass through the gastrointestinal tract and undergo bacterial fermentation in the cecum and large intestine

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However, body composition changes from successful fat loss can affect insulin sensitivity independently

Some centres extend this to six months or beyond, but only where clinically indicated for example, in patients with ongoing reflux symptoms or confirmed gastro-oesophageal reflux disease (GORD)