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A 2026 systematic review in eClinicalMedicine corroborated this trajectory, finding consistent and clinically meaningful rebound across body weight, waist circumference, glycemic control, and blood pressure after discontinuation

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In addition to our included studies, there were more original studies excluded from our meta-analysis due to methodological differences and a lack of appropriate data, which provide additional support for GLP-1RAs role in reducing alcohol consumption

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