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Through the presence of divalent metal transporter protein 1 (DMT1, also known as soluble protein carrier [SLC11A2]) and ZRT,IRT-related protein 14 (ZIP14, also known as SLC39A14), Fe 2+ can be transferred into the cytoplasm as an unstable iron pool (LIP) (72)

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Endocrinology 158 (8), 24272435

This mutation allows BirA to covalently label specific lysine residues on the surface of target proteins with biotin-5-AMP, selectively biotinylated acetyl-CoA carboxylase