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Like its companion BP-157, its a naturally occurring peptide that your body already manufactures in small amounts

From speculation to testing Rather than responding with opinion, the claim was evaluated through direct analysis

DOI: 10.3390/ijms19071987 BPC-157 angiogenic signaling VEGFR2AkteNOS activation, nitric oxide bioavailability, FAK-paxillin cell-anchoring cascade, anti-cytokine modulation: PMC8275860 TB-4 / TB-500 G-actin sequestration and threshold-saturation mechanism actin-monomer binding, cytoskeletal mobilization for cell migration, mass-action pharmacodynamics requiring bolus dosing: PubMed 12581423 TB-4 Ac-SDKP anti-fibrotic fragment N-terminal tetrapeptide (fragment 14) released by meprin- and POP processing

This enzyme is tryptophan 2,3-dioxygenase which is encoded by the TDO2 gene

discussion 771-2.