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Heres what we think we know for sure: GLP-1 drugs stimulate the production of insulin (which reduces blood sugar) and suppress the release of glucagon (which tends to raise blood sugar)

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For comparison, Lillys oral GLP-1 Foundayo demonstrated a 23% lower risk of major cardiovascular events (MACE-3 secondary endpoint) versus insulin glargine in the ACHIEVE-4 trial, per Dr