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5.4 GLP-1s anti-apoptotic effects GLP-1 RAs exhibit strong anti-apoptotic effects by activating the PI3K/Akt pathway, which promotes cell survival by inhibiting pro-apoptotic factors such as Bax and caspase-3, while upregulating anti-apoptotic proteins like Bcl-2 (104106)

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PYC has demonstrated substantial anticancer potential in various in vitro and in vivo models, supporting its role as a natural chemopreventive and therapeutic agent

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