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Because of this challenge to weight maintenance, it is important to develop adjunctive treatments to support patients in achieving their sustained weight-loss goals

Proinflammatory cytokines such as interferon- (IFN-), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-) play a key role in this immune-mediated destruction [24]

Groups 8 and 9: rats were fed on basal diet and 15% and 30% sweet color

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Together , these peptides are being studied for enhanced, synergistic effects in models of obesity , insulin resistance , and type 2 diabetes