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Activation of the aryl hydrocarbon receptor alleviates Sjgren's syndrome by promoting Bregs differentiation

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Proc Natl Acad Sci USA 96 : 73247329 Yakar S et al

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If there is insufficient (or no) B12 in bloodstream, or it is not linking well with B12 at this stage, your MMA will increase in your bloodstream, and carry on increasing until B12 makes the journey and the required links