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Metformin and the risk of neurodegenerative diseases in patients with diabetes: a meta-analysis of population-based cohort studies

It is reported that pharmacological treatment of PD with DRT plausibly plays a role on glucose metabolism, with the finding that in animal model levodopa and DA can suppress glucose-dependent pancreatic islets secretion by reducing the frequency of intracellular calcium current oscillation, thus representing a DA-ergic negative feedback on insulin secretion (Ustione and Piston, 2012)

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Iron : iron deficiency impairs thyroid metabolism