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3.2.1.2 Capsaicin Capsaicin, the primary bioactive compound from red chili peppers (Liu et al., 2022d), exhibits therapeutic effects on kidney in various animal models, such as UUO (Liu et al., 2022d), DKD (Ros-Silva et al., 2018) and nephrotoxicity (Jung et al., 2014)

Notably, LPS infiltration exacerbated insulin resistance and diabetes and led to various diabetic complications (Cani et al., 2007

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GLP-1 receptor agonists have shown the ability to reduce neuroinflammation and oxidative stresswell-recognized contributors to Alzheimers diseaseand provide neurotrophic effects in animal models of Alzheimers, the authors write, while cautioning that this needs to be verified by further clinical trials