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Since the ultimate goal of the project was to produce a clinically relevant molecule that could be delivered peripherally but still exhibit pro-cognitive/anti-dementia activity, the effectiveness of both the intraperitoneal and oral delivery routes of dihexa administration were determined using the scopolamine model

Klee, G

The cell viability was indirectly determined by examining the ratio of the absorbance value of metformin/ H 2 O 2 -treated cells relative to the control cells

Quantitative analysis was performed using ImageJ/Fiji with the SNT (Simple Neurite Tracer) plugin