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Results GEP44 binds to and activates GLP-1R, Y1-R, and Y2-R via biased agonism The addition of GEP44 to H188-GLP-1R transduced HEK293 cells resulted in elevated levels of cAMP with an EC 50 value of 417 pM (Fig

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Int J Pharm Pract 20:48

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Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Asano Y., Hiramoto T., Nishino R., Aiba Y., Kimura T., Yoshihara K., Koga Y., Sudo N

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Diabetes Care (2017) 40:3018

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