For now, the take-home messages for an informed patient or provider are: GLP-1 RAs (Ozempic, Wegovy, Mounjaro, etc.) are highly effective for T2D and obesity, offering glycemic control and substantial weight loss along with protective effects on the heart and possibly kidneys
We asked experts to explain everything you need to know about this research, including what this gene could mean for you and alternatives that may help you manage your health conditions or support weight loss
Third, weight loss associated with GLP-1 receptor agonists may reduce adipose-driven inflammation
Track results throughout maintenance phase
In BMAL1-knockout mice, pericytes progressively detach, extracellular matrix deposition is reduced, and tight junctions disassemble, leading to unstable neovasculature and loss of BBB integrity (79)