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Among these techniques, Fibroscan has demonstrated superiority over US in clinical diagnosis due to its ability to quantitatively assess both liver fat and fibrosis (67)

Potential interventions to mitigate immunosenescence, including reshaping immune organs, targeting different immune cells or signaling pathways, and nutritional and lifestyle interventions, are summarized

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- Decreased cancers could improve the cost-effectiveness calculations on GLP-1 drugs for obesity, although at current high acquisition prices they are still highly unlikely to be cost-saving

If symptoms do not improve despite adequate B12 replacement, further investigation for other causes of nerve pain will be necessary