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Lipid profile improvements (TRIUMPH-4): Non-HDL cholesterol: Clinically meaningful reduction Triglycerides: Significant reduction hsCRP (inflammatory marker): Significant reduction HDL cholesterol: Not significantly improved (consistent with Phase 2 findings) The triglyceride reduction is particularly notable and likely related to glucagon receptor activation, which enhances fat oxidation

Testosterone replacement (for women on low-dose T) supports muscle protein synthesis and lean tissue retention during a deficit

Gradual return of original conditions Appetite control is usually the first change patients notice

Local manufacturing clusters in Jiangsu and Guangdong expanded production through tech transfer agreements with multinational firms

Some are already shifting to older, less expensive GLP-1 agonists