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soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm

soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm Reduces CV Events in T2DM – (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine 🧪 T2DM + ASCVD/CKD 💊 Oral semaglutide 14 mg vs placebo 📉 SOUL trial shows oral semaglutide

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Due to the wide distribution of GLP-1R, GLP-1RAs also have a wide range of pharmacological effects

soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm Reduces CV Events in T2DM  (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine  T2DM + ASCVD/CKD  Oral semaglutide 14 mg vs placebo  SOUL trial shows oral semaglutide

I conclude with a discussion of policy around bulk manufacturing of semaglutide and other drugs without an established product quality reference standard

soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm Reduces CV Events in T2DM  (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine  T2DM + ASCVD/CKD  Oral semaglutide 14 mg vs placebo  SOUL trial shows oral semaglutide

R.Blasco ConesaM

soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm Reduces CV Events in T2DM  (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine  T2DM + ASCVD/CKD  Oral semaglutide 14 mg vs placebo  SOUL trial shows oral semaglutide

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soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm Reduces CV Events in T2DM  (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine  T2DM + ASCVD/CKD  Oral semaglutide 14 mg vs placebo  SOUL trial shows oral semaglutide

The 24% figure from retatrutide Phase 2, over a shorter timeframe, is meaningfully ahead of both

soul trial oral semaglutide cardiovascular outcomes results 2024 2025 nejm Reduces CV Events in T2DM  (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine  T2DM + ASCVD/CKD  Oral semaglutide 14 mg vs placebo  SOUL trial shows oral semaglutide
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