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RAS mutations reduce the efficacy of anti-epidermal growth factor receptor (EGFR) monoclonal antibodies combined with chemotherapy in metastatic colorectal cancer patients

For quantification of islets number of digested WT and GRK2+/ pancreata, isolated islets were counted manually by microscopic observation after separation of the surrounding acinar tissue

For example, NMR-titration experiments of non-glutathionylated poplar GrxC4 or ScGrx8 with GSH required high glutathione concentrations to detect chemical shifts 47,48 (and titrations of active site serine mutants with GSSG cannot discriminate between both glutathionyl moieties)

The role of vaginal microbiota is also critically important in the context of HIV