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4.4 Vitamins It came to light that pre-treatment with an antioxidant mixture comprising of vitamin C, vitamin E, and beta-carotene, at various doses, enhanced chemotherapeutic effects of paclitaxel and carboplatin, as indicated by a notable improvement in the severity of apoptosis in cancer cell lines [258]

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Furthermore, studies have examined these effects in fibroblast and keratinocyte cultures, endothelial and neuronal systems, and preclinical animal models related to wound repair and tissue response

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