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The table below summarizes these mechanisms and their clinical reach

A good rule of thumb is to divide your plate into three sections

Substantial empirical work is still needed to validate these mechanisms, determine causality, and assess their relevance for clinical practice

But the agency is a little hamstrung: if there is evidence that a drug is useful for the purpose being advertised, even if the drug isnt FDA-approved for that purpose, the FTC wont act, Sklar says