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The peptide's effects on memory consolidation appear mediated through enhanced hippocampal long-term potentiation (LTP), the neurophysiological basis of memory storage, with Dihexa treatment increasing both the magnitude and persistence of synaptic strengthening

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(2012) Neuroprotection with an erythropoietin mimetic peptide (pHBSP) in a model of mild traumatic brain injury complicated by hemorrhagic shock