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concurrent tobacco smoking further augments thrombotic risk, and careful monitoring is advised when estrogens are co-administered with thyroid hormones, corticosteroids, or anticoagulants due to possible alterations in binding protein levels and pharmacodynamic response
Vitamin B12 Deficiency: Recognition and Management
This has led some researchers to target 9mg rather than 12mg as their maintenance dose, especially given that the difference (2.3 percentage points) may not justify the additional side effect burden for all individuals
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