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Preclinical investigations have shown that these agents downregulate proprotein convertase subtilisin/kexin type 9 (PCSK9) expression, upregulate low-density lipoprotein receptor (LDLR) levels, and suppress postprandial secretion of triglycerides and chylomicrons (87, 88)

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Yu S, Long H, Lyu QF, Zhang QH, Yan ZG, Liang HX, et al

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