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For instance, the administration of glucagon receptor antagonists increased hepatic fat content and plasma concentrations of LDL-cholesterol in people with type 2 diabetes [51]

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retatrutide data are at 48 weeks only Population differences : Participant demographics, baseline BMI, and comorbidity profiles may differ Dose optimization : Retatrutide's Phase 3 may use different doses than Phase 2 A head-to-head randomized trial would be needed to definitively establish relative efficacy

Understanding the trial results at each dose level helps you set realistic expectations and choose the right maintenance dose for your goals