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Since oxidative stress is closely linked to DNA damage, the study also examined the extent of DNA lesions by quantifying H2AX, a marker of DNA double-strand breaks

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So Sam Rhee: how about the other now, um, just to sum, like there's another, when people call, talk about peptides

Increased signaling through exchange proteins directly activated by cAMP (EPACs), specifically EPAC2, and activation of protein kinase A (PKA) follow the rise in cAMP